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cona corona [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42213, updated on 4-Jan-2025

Summary

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Official Symbol
conaprovided by FlyBase
Official Full Name
coronaprovided by FlyBase
Primary source
FLYBASE:FBgn0038612
Locus tag
Dmel_CG7676
See related
AllianceGenome:FB:FBgn0038612
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG7676; Cona; CONA; Dmel\CG7676
Summary
Involved in synaptonemal complex assembly. Located in synaptonemal complex. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See cona in Genome Data Viewer
Location:
91A5-91A5; 3-63 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18385828..18386887)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14211550..14212609)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Vacuolar H[+] ATPase 100kD subunit 4 Neighboring gene Vacuolar H[+] ATPase 100kD subunit 2 Neighboring gene Vesicle transport through interaction with t-SNAREs 1b Neighboring gene WD repeat domain 37

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Synaptonemal complex components promote centromere pairing in pre-meiotic germ cells. Christophorou N, et al. PLoS Genet, 2013. PMID 24367278, Free PMC Article
  2. Unconventional conservation reveals structure-function relationships in the synaptonemal complex. Kursel LE, et al. Elife, 2021 Nov 17. PMID 34787570, Free PMC Article
  3. Corolla is a novel protein that contributes to the architecture of the synaptonemal complex of Drosophila. Collins KA, et al. Genetics, 2014 Sep. PMID 24913682, Free PMC Article
  4. Couples, pairs, and clusters: mechanisms and implications of centromere associations in meiosis. Obeso D, et al. Chromosoma, 2014 Mar. PMID 24126501, Free PMC Article
  5. Uncharted territories: Solving the mysteries of male meiosis in flies. Lee L, et al. PLoS Genet, 2024 Mar. PMID 38489251, Free PMC Article

See all (47) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CONA is required for the stable 'zippering' of transverse filaments to form the central region of the Drosophila synaptonemal complex.
    Title: Corona is required for higher-order assembly of transverse filaments into full-length synaptonemal complex in Drosophila oocytes.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in homologous chromosome pairing at meiosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in synaptonemal complex assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in synaptonemal complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
corona
Names
CG7676-PA
cona-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    18385828..18386887
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142462.3 → NP_650719.2  corona [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650719.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    B6UW98, Q4V4C0, Q9VE78
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VE78 Q9VE78

Gene LinkOut

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