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Glut3 Glucose transporter type 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42036, updated on 17-Dec-2024

Summary

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Official Symbol
Glut3provided by FlyBase
Official Full Name
Glucose transporter type 3provided by FlyBase
Primary source
FLYBASE:FBgn0015230
Locus tag
Dmel_CG3853
See related
AllianceGenome:FB:FBgn0015230
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG3853; Dmel\CG3853; GLU; Glut; glut 3; Glut-3; glut-l
Summary
Predicted to enable D-glucose binding activity and D-glucose transmembrane transporter activity. Predicted to be involved in D-glucose transmembrane transport. Predicted to be located in plasma membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Glut3 in Genome Data Viewer
Location:
89E1-89E1; 3-59 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (16788311..16790021)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (12614033..12615743)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene bithoraxoid Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44945 Neighboring gene long non-coding RNA:CR45750 Neighboring gene long noncoding RNA: testis-specific 16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Copy-number variation of the neuronal glucose transporter gene SLC2A3 and age of onset in Huntington's disease. Vittori A, et al. Hum Mol Genet, 2014 Jun 15. PMID 24452335, Free PMC Article
  2. The border between the ultrabithorax and abdominal-A regulatory domains in the Drosophila bithorax complex. Bender W, et al. Genetics, 2013 Apr. PMID 23288934, Free PMC Article
  3. Atractylodes macrocephala Koidz. and Cuscuta chinensis Lam. extract relieves insulin resistance via PI3K/Akt signalling in diabetic Drosophila. Li Y, et al. J Tradit Complement Med, 2024 Jul. PMID 39035690, Free PMC Article
  4. Mathematical model to predict regions of chromatin attachment to the nuclear matrix. Singh GB, et al. Nucleic Acids Res, 1997 Apr 1. PMID 9060438, Free PMC Article
  5. Neural circuit mechanisms encoding motivational states in Drosophila. Lee SS, et al. Curr Opin Neurobiol, 2020 Oct. PMID 32563845, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables D-glucose binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables D-glucose transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables sugar transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in D-glucose transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in carbohydrate transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
glucose transporter type 3
Names
CG3853-PA
Glut3-PA
glucose transporter-like

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    16788311..16790021
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_080484.3 → NP_536732.1  glucose transporter type 3 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_536732.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P53403, Q8T4C0, Q9VER2
    UniProtKB/TrEMBL
    H0RNJ2
    Related
    FBpp0082790
    Conserved Domains (2) summary
    cd06174
    Location:63 → 226
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:60 → 484
    Sugar_tr; Sugar (and other) transporter
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53403.1 P53403

Gene LinkOut

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