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Dhfr - Dihydrofolate reductase

Enables dihydrofolate reductase activity. Predicted to be involved in dihydrofolate metabolic process; folic acid metabolic process; and tetrahydrofolate biosynthetic process. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Orthologous to human DHFR (dihydrofolate reductase); DHFR2 (dihydrofolate reductase 2); and DHFRP1 (dihydrofolate reductase pseudogene 1). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to Dhfr

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Species Gene Architecture aa