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Sb - Stubble

Predicted to enable serine-type endopeptidase activity. Involved in actin filament bundle assembly and wing disc development. Predicted to be located in plasma membrane. Is expressed in imaginal disc; leg; wing; wing anterior compartment; and wing pouch. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 11. Orthologous to human ST14 (ST14 transmembrane serine protease matriptase); TMPRSS13 (transmembrane serine protease 13); and TMPRSS2 (transmembrane serine protease 2). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa