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CG10185 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41953, updated on 9-Dec-2024

Summary

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Official Symbol
CG10185provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038397
Locus tag
Dmel_CG10185
See related
AllianceGenome:FB:FBgn0038397
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG10185
Summary
Orthologous to human NWD2 (NACHT and WD repeat domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG10185 in Genome Data Viewer
Location:
89B2-89B2; 3-58 cM
Exon count:
12
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (16060589..16067594, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11886311..11893316, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45212 Neighboring gene I-kappaB kinase beta Neighboring gene uncharacterized protein Neighboring gene mini spindles Neighboring gene Myosin heavy chain-like Neighboring gene uncharacterized protein Neighboring gene sex-specific enzyme 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Cyclically Seasonal Drosophila subobscura Inversion O(7) Originated From Fragile Genomic Sites and Relocated Immunity and Metabolic Genes. Karageorgiou C, et al. Front Genet, 2020. PMID 33193649, Free PMC Article
  2. Accelerated sequence divergence of conserved genomic elements in Drosophila melanogaster. Holloway AK, et al. Genome Res, 2008 Oct. PMID 18583644, Free PMC Article
  3. Functional relevance of genes predicted to be affected by epigenetic alterations in atypical teratoid/rhabdoid tumors. Tegeder I, et al. J Neurooncol, 2019 Jan. PMID 30446899
  4. Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. Krauchunas AR, et al. Dev Biol, 2012 Oct 1. PMID 22884528, Free PMC Article
  5. Genome-wide identification and characterization of tissue-specific RNA editing events in D. melanogaster and their potential role in regulating alternative splicing. Mazloomian A, et al. RNA Biol, 2015. PMID 26512413, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10185-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    16060589..16067594 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142264.3 → NP_650521.1  uncharacterized protein Dmel_CG10185 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650521.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VEZ2
    Related
    FBpp0082689
    Conserved Domains (4) summary
    COG2319
    Location:1177 → 1379
    WD40; WD40 repeat [General function prediction only]
    pfam13191
    Location:363 → 488
    AAA_16; AAA ATPase domain
    sd00039
    Location:1214 → 1256
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:1216 → 1380
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VEZ2 Q9VEZ2

Gene LinkOut

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