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CG3631 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41797, updated on 4-Jan-2025

Summary

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Official Symbol
CG3631provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038268
Locus tag
Dmel_CG3631
See related
AllianceGenome:FB:FBgn0038268
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG3631
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in proteoglycan biosynthetic process. Located in Golgi apparatus and endoplasmic reticulum. Is expressed in adult fat body and spermatozoon. Orthologous to human FAM20B (FAM20B glycosaminoglycan xylosylkinase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG3631 in Genome Data Viewer
Location:
88D6-88D6; 3-56 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14879457..14882631)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10705179..10708353)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene bitesize Neighboring gene long non-coding RNA:CR46024 Neighboring gene uncharacterized protein Neighboring gene Rrp6 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cyclin C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Raine syndrome protein FAM20C is a Golgi kinase that phosphorylates bio-mineralization proteins. Ishikawa HO, et al. PLoS One, 2012. PMID 22900076, Free PMC Article
  2. LTR-mediated retroposition as a mechanism of RNA-based duplication in metazoans. Tan S, et al. Genome Res, 2016 Dec. PMID 27934698, Free PMC Article
  3. TRF4 is involved in polyadenylation of snRNAs in Drosophila melanogaster. Nakamura R, et al. Mol Cell Biol, 2008 Nov. PMID 18765642, Free PMC Article
  4. Genome-wide analysis of retrogene polymorphisms in Drosophila melanogaster. Schrider DR, et al. Genome Res, 2011 Dec. PMID 22135405, Free PMC Article
  5. The circadian clock interacts with metabolic physiology to influence reproductive fitness. Xu K, et al. Cell Metab, 2011 Jun 8. PMID 21641546, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables phosphotransferase activity, alcohol group as acceptor IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteoglycan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG3631-PC
CG3631-PD
CG3631-PE
NP_650398.3
NP_731951.2
NP_996212.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    14879457..14882631
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_206490.3 → NP_996212.1  uncharacterized protein Dmel_CG3631, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996212.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q95T10
    Conserved Domains (1) summary
    cl05973
    Location:224 → 414
    FAM20_C_like; C-terminal putative kinase domain of FAM20 (family with sequence similarity 20), Drosophila Four-jointed (Fj), and related proteins

  2. NM_142141.3 → NP_650398.3  uncharacterized protein Dmel_CG3631, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650398.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q95T10
    Conserved Domains (1) summary
    cl05973
    Location:224 → 414
    FAM20_C_like; C-terminal putative kinase domain of FAM20 (family with sequence similarity 20), Drosophila Four-jointed (Fj), and related proteins

  3. NM_169605.3 → NP_731951.2  uncharacterized protein Dmel_CG3631, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_731951.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q95T10
    Conserved Domains (1) summary
    cl05973
    Location:224 → 414
    FAM20_C_like; C-terminal putative kinase domain of FAM20 (family with sequence similarity 20), Drosophila Four-jointed (Fj), and related proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q95T10.1 Q95T10

Gene LinkOut

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