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CG14855 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41789, updated on 4-Jan-2025

Summary

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Official Symbol
CG14855provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038260
Locus tag
Dmel_CG14855
See related
AllianceGenome:FB:FBgn0038260
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG14855
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Lynch syndrome and mismatch repair cancer syndrome. Orthologous to several human genes including SLC22A10 (solute carrier family 22 member 10); SLC22A11 (solute carrier family 22 member 11); and SLC22A12 (solute carrier family 22 member 12). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG14855 in Genome Data Viewer
Location:
88D3-88D3; 3-56 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14796305..14798474)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10622027..10624196)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Senescence marker protein-30 Neighboring gene javelin-like Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene bitesize

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila SLC22 Orthologs Related to OATs, OCTs, and OCTNs Regulate Development and Responsiveness to Oxidative Stress. Engelhart DC, et al. Int J Mol Sci, 2020 Mar 15. PMID 32183456, Free PMC Article
  2. Blue light induces a neuroprotective gene expression program in Drosophila photoreceptors. Hall H, et al. BMC Neurosci, 2018 Jul 20. PMID 30029619, Free PMC Article
  3. A single-cell transcriptomic atlas of complete insect nervous systems across multiple life stages. Corrales M, et al. Neural Dev, 2022 Aug 24. PMID 36002881, Free PMC Article
  4. The Drosophila blood-brain barrier: development and function of a glial endothelium. Limmer S, et al. Front Neurosci, 2014. PMID 25452710, Free PMC Article
  5. RNA-seq reveals post-transcriptional regulation of Drosophila insulin-like peptide dilp8 and the neuropeptide-like precursor Nplp2 by the exoribonuclease Pacman/XRN1. Jones CI, et al. Nucleic Acids Res, 2016 Jan 8. PMID 26656493, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG14855-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    14796305..14798474
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142133.4 → NP_650390.2  uncharacterized protein Dmel_CG14855 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650390.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VFG2
    Related
    FBpp0082450
    Conserved Domains (2) summary
    cd06174
    Location:127 → 499
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:11 → 507
    2A0119; cation transport protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SYJ3 Q8SYJ3
Q9VFG2 Q9VFG2

Gene LinkOut

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Miscellaneous