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CG7987 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41768, updated on 9-Dec-2024

Summary

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Official Symbol
CG7987provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038244
Locus tag
Dmel_CG7987
See related
AllianceGenome:FB:FBgn0038244
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0118547.245; Dmel\CG7987
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; embryonic/larval midgut primordium; gut section; and mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG7987 in Genome Data Viewer
Location:
88C6-88C6; 3-55 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14570472..14575887, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10396194..10401609, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44095 Neighboring gene uncharacterized protein Neighboring gene Cystatin-like Neighboring gene uncharacterized protein Neighboring gene stumps Neighboring gene long non-coding RNA:CR46153

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional relevance of genes predicted to be affected by epigenetic alterations in atypical teratoid/rhabdoid tumors. Tegeder I, et al. J Neurooncol, 2019 Jan. PMID 30446899
  2. Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen. Brody T, et al. Mech Dev, 2002 Apr. PMID 11900973
  3. A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development. Schertel C, et al. Genome Res, 2015 Apr. PMID 25568052, Free PMC Article
  4. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article
  5. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7987-PA
CG7987-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    14570472..14575887 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142118.2 → NP_650375.1  uncharacterized protein Dmel_CG7987, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650375.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q29R10
    Related
    FBpp0082437
    Conserved Domains (6) summary
    COG5048
    Location:326 → 734
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:620 → 640
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:534 → 554
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00020
    Location:709 → 726
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:661 → 685
    zf-H2C2_2; Zinc-finger double domain
    pfam13694
    Location:921 → 1017
    Hph; Sec63/Sec62 complex-interacting family

  2. NM_169587.2 → NP_731922.1  uncharacterized protein Dmel_CG7987, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_731922.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q29R10
    Related
    FBpp0082438
    Conserved Domains (6) summary
    COG5048
    Location:326 → 734
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:620 → 640
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:534 → 554
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00020
    Location:709 → 726
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:661 → 685
    zf-H2C2_2; Zinc-finger double domain
    pfam13694
    Location:921 → 1017
    Hph; Sec63/Sec62 complex-interacting family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q29R10 Q29R10
Q8T3L3 Q8T3L3

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