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CG8461 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41758, updated on 9-Dec-2024

Summary

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Official Symbol
CG8461provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038235
Locus tag
Dmel_CG8461
See related
AllianceGenome:FB:FBgn0038235
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8461
Summary
Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of 90S preribosome. Predicted to be active in nucleolus. Is expressed in several structures, including embryonic/larval midgut; embryonic/larval midgut primordium; fat body primordium; larval muscle system; and trunk mesoderm. Orthologous to human RRP36 (ribosomal RNA processing 36). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG8461 in Genome Data Viewer
Location:
88C3-88C3; 3-55 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14512639..14513637, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10338361..10339359, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44177 Neighboring gene HTRA2-related serine protease Neighboring gene mitochondrial ribosomal protein L11 Neighboring gene Phosphodiesterase 6 Neighboring gene uncharacterized protein Neighboring gene Cytochrome P450 313a1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Alternative germ cell death pathway in Drosophila involves HtrA2/Omi, lysosomes, and a caspase-9 counterpart. Yacobi-Sharon K, et al. Dev Cell, 2013 Apr 15. PMID 23523076
  2. Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi. Neumüller RA, et al. Cell Stem Cell, 2011 May 6. PMID 21549331, Free PMC Article
  3. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Dunn JG, et al. Elife, 2013 Dec 3. PMID 24302569, Free PMC Article
  4. Transcription factor networks in Drosophila melanogaster. Rhee DY, et al. Cell Rep, 2014 Sep 25. PMID 25242320, Free PMC Article
  5. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of 90S preribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8461-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    14512639..14513637 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142110.5 → NP_650367.1  uncharacterized protein Dmel_CG8461 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650367.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95RH5, Q9VFJ1
    Related
    FBpp0082445
    Conserved Domains (1) summary
    pfam06102
    Location:72 → 232
    DUF947; Domain of unknown function (DUF947)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VFJ1 Q9VFJ1

Gene LinkOut

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