Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search NCBI

trx - trithorax

Enables several functions, including protein homodimerization activity; protein methyltransferase activity; and protein phosphatase 1 binding activity. Involved in several processes, including germ cell migration; haltere development; and positive regulation of transcription elongation by RNA polymerase II. Located in nucleus and polytene chromosome band. Part of MLL1/2 complex; histone acetyltransferase complex; and transcription elongation factor complex. Is expressed in several structures, including epithelium; ganglia; gut section; head epidermis primordium; and imaginal disc. Used to study congenital heart disease. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder; cervical cancer; dystonia 28, childhood-onset; gastrointestinal system cancer (multiple); and hematologic cancer (multiple). Orthologous to human KMT2A (lysine methyltransferase 2A) and KMT2B (lysine methyltransferase 2B). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to trx

NCBI Orthologs

How was this calculated?

genes for:

Protein alignment

Align

Download data

Download
Species Gene Architecture aa