U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG12402 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41714, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
CG12402provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038202
Locus tag
Dmel_CG12402
See related
AllianceGenome:FB:FBgn0038202
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG12402; FBXL11
Summary
Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CG12402 in Genome Data Viewer
Location:
88A8-88A8; 3-54 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14104488..14108321, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (9930210..9934043, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR46531 Neighboring gene Pyrokinin 1 receptor Neighboring gene antisense RNA:CR44237 Neighboring gene Odorant receptor 88a Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A conserved F-box gene with unusual transcript localization. Das T, et al. Dev Genes Evol, 2002 Apr. PMID 11976951
  2. F-box proteins: the key to protein degradation. Ho MS, et al. J Biomed Sci, 2006 Mar. PMID 16463014
  3. A systematic phenotypic screen of F-box genes through a tissue-specific RNAi-based approach in Drosophila. Dui W, et al. J Genet Genomics, 2012 Aug 20. PMID 22884096
  4. Defining components of the ß-catenin destruction complex and exploring its regulation and mechanisms of action during development. Roberts DM, et al. PLoS One, 2012. PMID 22359584, Free PMC Article
  5. Control of protein degradation by E3 ubiquitin ligases in Drosophila eye development. Ou CY, et al. Trends Genet, 2003 Jul. PMID 12850443

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISM
Inferred from Sequence Model
more info
  
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SCF ubiquitin ligase complex ISM
Inferred from Sequence Model
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG12402-PA
CG12402-PB
CG12402-PC

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    14104488..14108321 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142078.3 → NP_650335.1  uncharacterized protein Dmel_CG12402, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650335.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VFN3
    Related
    FBpp0082374
    Conserved Domains (4) summary
    cd09293
    Location:430 → 595
    AMN1; Antagonist of mitotic exit network protein 1
    cd00116
    Location:297 → 482
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:412 → 437
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam00646
    Location:75 → 117
    F-box; F-box domain

  2. NM_001275629.1 → NP_001262558.1  uncharacterized protein Dmel_CG12402, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262558.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KHI0
    Conserved Domains (4) summary
    cd09293
    Location:430 → 595
    AMN1; Antagonist of mitotic exit network protein 1
    cd00116
    Location:297 → 482
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:412 → 437
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam00646
    Location:75 → 117
    F-box; F-box domain

  3. NM_001316552.1 → NP_001303481.1  uncharacterized protein Dmel_CG12402, isoform C [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A126GUT7
    Conserved Domains (4) summary
    cd09293
    Location:430 → 595
    AMN1; Antagonist of mitotic exit network protein 1
    cd00116
    Location:297 → 482
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:412 → 437
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam00646
    Location:75 → 117
    F-box; F-box domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4KHI0 A0A0B4KHI0
A0A126GUT7 A0A126GUT7
Q9VFN3 Q9VFN3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools