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CG9920 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41712, updated on 4-Jan-2025

Summary

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Official Symbol
CG9920provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038200
Locus tag
Dmel_CG9920
See related
AllianceGenome:FB:FBgn0038200
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0140519.48; BEST:GH20473; Dmel\CG9920
Summary
Predicted to enable metal ion binding activity; protein-folding chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding. Predicted to be active in mitochondrial matrix. Is expressed in adult head. Orthologous to human HSPE1 (heat shock protein family E (Hsp10) member 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG9920 in Genome Data Viewer
Location:
88A8-88A8; 3-54 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14097293..14098080, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (9923015..9923802, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Niemann-Pick type C-2b Neighboring gene CCHamide-1 Neighboring gene long non-coding RNA:CR46531 Neighboring gene Pyrokinin 1 receptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CG9920 is necessary for mitochondrial morphogenesis and individualization during spermatogenesis in Drosophila melanogaster. Li C, et al. Dev Biol, 2024 Aug. PMID 38703942
  2. In vivo interaction proteomics reveal a novel p38 mitogen-activated protein kinase/Rack1 pathway regulating proteostasis in Drosophila muscle. Belozerov VE, et al. Mol Cell Biol, 2014 Feb. PMID 24277934, Free PMC Article
  3. Muscle mitohormesis promotes longevity via systemic repression of insulin signaling. Owusu-Ansah E, et al. Cell, 2013 Oct 24. PMID 24243023, Free PMC Article
  4. Sex-specific role of Drosophila melanogaster HP1 in regulating chromatin structure and gene transcription. Liu LP, et al. Nat Genet, 2005 Dec. PMID 16258543
  5. Heat-shock promoters: targets for evolution by P transposable elements in Drosophila. Walser JC, et al. PLoS Genet, 2006 Oct 6. PMID 17029562, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein folding chaperone IEA
Inferred from Electronic Annotation
more info
  
enables protein-folding chaperone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in chaperone cofactor-dependent protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein folding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG9920-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    14097293..14098080 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142076.3 → NP_650333.1  uncharacterized protein Dmel_CG9920 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650333.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VFN5
    Related
    FBpp0082377
    Conserved Domains (1) summary
    smart00883
    Location:7 → 101
    Cpn10; Chaperonin 10 Kd subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VFN5 Q9VFN5

Gene LinkOut

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