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CG3061 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41707, updated on 17-Dec-2024

Summary

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Official Symbol
CG3061provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038195
Locus tag
Dmel_CG3061
See related
AllianceGenome:FB:FBgn0038195
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG3061
Summary
Predicted to enable Hsp70 protein binding activity. Predicted to be involved in cellular response to misfolded protein and chaperone cofactor-dependent protein refolding. Located in endomembrane system. Is expressed in adult head and organism. Orthologous to several human genes including DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG3061 in Genome Data Viewer
Location:
88A4-88A4; 3-54 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14032371..14035041)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (9858093..9860763)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR43460 Neighboring gene roadkill Neighboring gene transfer RNA:Serine-GCT 2-2 Neighboring gene Cytochrome P450 6d5 Neighboring gene uncharacterized protein Neighboring gene forkhead box, sub-group O

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Discovery of insect and human dengue virus host factors. Sessions OM, et al. Nature, 2009 Apr 23. PMID 19396146, Free PMC Article
  2. The Cyclically Seasonal Drosophila subobscura Inversion O(7) Originated From Fragile Genomic Sites and Relocated Immunity and Metabolic Genes. Karageorgiou C, et al. Front Genet, 2020. PMID 33193649, Free PMC Article
  3. Life extension in Drosophila by feeding a drug. Kang HL, et al. Proc Natl Acad Sci U S A, 2002 Jan 22. PMID 11792861, Free PMC Article
  4. Two novel DnaJ chaperone proteins CG5001 and P58IPK regulate the pathogenicity of Huntington's disease related aggregates. Deo A, et al. Sci Rep, 2024 Sep 6. PMID 39242711, Free PMC Article
  5. RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology. Raut S, et al. G3 (Bethesda), 2017 Jul 5. PMID 28500055, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables Hsp70 protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cellular response to misfolded protein IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in chaperone cofactor-dependent protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in endomembrane system HDA PubMed 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG3061-PA
dnaJ like2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    14032371..14035041
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142071.3 → NP_650328.1  uncharacterized protein Dmel_CG3061 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650328.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VFP0
    Related
    FBpp0082332
    Conserved Domains (3) summary
    COG0484
    Location:105 → 224
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    pfam00226
    Location:106 → 167
    DnaJ; DnaJ domain
    pfam09320
    Location:269 → 366
    DUF1977; Domain of unknown function (DUF1977)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VFP0 Q9VFP0

Gene LinkOut

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