sqd - squid

Predicted to enable RNA binding activity. Involved in negative regulation of RNA splicing and oogenesis. Located in chromatin; omega speckle; and polytene chromosome puff. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in several structures, including Y chromosome loop; adult brain cell body rind; adult head; adult heart; and germline cell. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 3 and hepatocellular carcinoma. Orthologous to several human genes including HNRNPD (heterogeneous nuclear ribonucleoprotein D). [provided by Alliance of Genome Resources, Dec 2024]

NCBI Orthologs

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