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MAPKAPK3 MAPK activated protein kinase 3 [ Gallus gallus (chicken) ]

Gene ID: 415917, updated on 3-Dec-2024

Summary

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Symbol
MAPKAPK3provided by CGNC
Full Name
MAPK activated protein kinase 3provided by CGNC
Primary source
CGNC:1627
See related
Ensembl:ENSGALG00010028146
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See MAPKAPK3 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 12 NC_052543.1 (1946874..1988947)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 12 NC_052584.1 (1984694..2026760)

Chromosome 12 - NC_052543.1Genomic Context describing neighboring genes Neighboring gene HemK methyltransferase family member 1 Neighboring gene uncharacterized LOC124417166 Neighboring gene cytokine inducible SH2 containing protein Neighboring gene uncharacterized LOC124417167 Neighboring gene dedicator of cytokinesis 3 Neighboring gene uncharacterized LOC121106620

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium/calmodulin-dependent protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mitogen-activated protein kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein autophosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to cytokine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
MAP kinase-activated protein kinase 3
Names
mitogen-activated protein kinase-activated protein kinase 3
NP_001308487.1
XP_025010225.1
XP_025010226.1
XP_040502114.1
XP_046782163.1
XP_046782164.1
XP_046782165.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001321558.2 → NP_001308487.1  MAP kinase-activated protein kinase 3

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000251
    UniProtKB/TrEMBL
    A0A8V1ACK0, E1BT35
    Related
    ENSGALP00010041943.1, ENSGALT00010068200.1
    Conserved Domains (1) summary
    cd14172
    Location:41 → 307
    STKc_MAPKAPK3; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 3

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052543.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    1946874..1988947
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025154458.3 → XP_025010226.1  MAP kinase-activated protein kinase 3 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2U1E9
    Conserved Domains (1) summary
    cd14172
    Location:41 → 307
    STKc_MAPKAPK3; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 3

  2. XM_040646180.2 → XP_040502114.1  MAP kinase-activated protein kinase 3 isoform X2

    UniProtKB/TrEMBL
    A0A8V1ACK0, E1BT35
    Conserved Domains (1) summary
    cd14172
    Location:41 → 307
    STKc_MAPKAPK3; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 3

  3. XM_025154457.3 → XP_025010225.1  MAP kinase-activated protein kinase 3 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2U1E9
    Related
    ENSGALP00010041941.1, ENSGALT00010068198.1
    Conserved Domains (1) summary
    cd14172
    Location:41 → 307
    STKc_MAPKAPK3; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 3

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052584.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    1984694..2026760
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046926208.1 → XP_046782164.1  MAP kinase-activated protein kinase 3 isoform X1

  2. XM_046926209.1 → XP_046782165.1  MAP kinase-activated protein kinase 3 isoform X2

    UniProtKB/TrEMBL
    A0A8V1ACK0

  3. XM_046926207.1 → XP_046782163.1  MAP kinase-activated protein kinase 3 isoform X1

Nucleotide Protein
Heading Accession and Version

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