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Dtg Dpp target gene [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41558, updated on 9-Dec-2024

Summary

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Official Symbol
Dtgprovided by FlyBase
Official Full Name
Dpp target geneprovided by FlyBase
Primary source
FLYBASE:FBgn0038071
Locus tag
Dmel_CG6234
See related
AllianceGenome:FB:FBgn0038071
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6234; Dmel\CG6234
Summary
Involved in gastrulation. Located in cell surface and vesicle. Is expressed in amnioserosa anlage; dorsal ectoderm; and presumptive wing vein. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Dtg in Genome Data Viewer
Location:
87C3-87C3; 3-52 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12648058..12652910)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8473780..8478632)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46351 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45586

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The oligomeric state of CtBP determines its role as a transcriptional co-activator and co-repressor of Wingless targets. Bhambhani C, et al. EMBO J, 2011 May 18. PMID 21468031, Free PMC Article
  2. SMAD dependent signaling plays a detrimental role in a fly model of SMARCB1-deficiency and the biology of atypical teratoid/rhabdoid tumors. Jeibmann A, et al. J Neurooncol, 2017 Feb. PMID 28108836
  3. Novel TCF-binding sites specify transcriptional repression by Wnt signalling. Blauwkamp TA, et al. EMBO J, 2008 May 21. PMID 18418383, Free PMC Article
  4. C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila. Fang M, et al. EMBO J, 2006 Jun 21. PMID 16710294, Free PMC Article
  5. Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor. Buechling T, et al. Curr Biol, 2010 Jul 27. PMID 20579883

See all (52) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in gastrulation IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IDA
Inferred from Direct Assay
more info
 PubMed 
located_in vesicle IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Dpp target gene
Names
CG6234-PA
Dtg-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    12648058..12652910
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141963.3 → NP_650220.2  Dpp target gene [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650220.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q960I9, Q9VG45
    Related
    FBpp0082117
    Conserved Domains (3) summary
    PTZ00341
    Location:112 → 325
    PTZ00341; Ring-infected erythrocyte surface antigen; Provisional
    PRK10811
    Location:303 → 445
    rne; ribonuclease E; Reviewed
    pfam11702
    Location:410 → 498
    DUF3295; Protein of unknown function (DUF3295)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q960I9 Q960I9
Q9VG45 Q9VG45

Gene LinkOut

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