ppil3 peptidylprolyl isomerase (cyclophilin)-like 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ppil3provided by ZNC
Official Full Name: peptidylprolyl isomerase (cyclophilin)-like 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-040625-159
See related: Ensembl:ENSDARG00000033370 AllianceGenome:ZFIN:ZDB-GENE-040625-159
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:86715
Summary: Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to act upstream of or within protein peptidyl-prolyl isomerization. Predicted to be part of catalytic step 2 spliceosome. Orthologous to human PPIL3 (peptidylprolyl isomerase like 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (64851990..64856033)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (64170826..64174869)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables isomerase activity	IEA Inferred from Electronic Annotation more info
enables peptidyl-prolyl cis-trans isomerase activity	IBA Inferred from Biological aspect of Ancestor more info
enables peptidyl-prolyl cis-trans isomerase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein folding	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein folding	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein peptidyl-prolyl isomerization	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of catalytic step 2 spliceosome	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: peptidyl-prolyl cis-trans isomerase-like 3

Names: ppil3b

NP_001002146.1

EC 5.2.1.8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002146.1 → NP_001002146.1 peptidyl-prolyl cis-trans isomerase-like 3

See identical proteins and their annotated locations for NP_001002146.1

Status: PROVISIONAL

Source sequence(s)

BC071392

UniProtKB/TrEMBL

A0A8M1MZZ8, Q6IQL3

Related

ENSDARP00000044646.5, ENSDART00000044647.6

Conserved Domains (1) summary

cd01928
Location:1 → 154

Cyclophilin_PPIL3_like; Cyclophilin_PPIL3_like. Proteins similar to Human cyclophilin-like peptidylprolyl cis- trans isomerase (PPIL3). Members of this family lack a key residue important for cyclosporin binding: the tryptophan residue corresponding to W121 in human hCyP-18a; ...