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rab1bb RAB1B, member RAS oncogene family b [ Danio rerio (zebrafish) ]

Gene ID: 415219, updated on 9-Dec-2024

Summary

Official Symbol
rab1bbprovided by ZNC
Official Full Name
RAB1B, member RAS oncogene family bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040625-133
See related
Ensembl:ENSDARG00000056479 AllianceGenome:ZFIN:ZDB-GENE-040625-133
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:86773; wu:fc83b07
Summary
Predicted to enable GTPase activity. Predicted to be involved in autophagosome assembly and intracellular protein transport. Predicted to be active in endomembrane system. Is expressed in central nervous system. Orthologous to several human genes including RAB1B (RAB1B, member RAS oncogene family). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See rab1bb in Genome Data Viewer
Location:
chromosome: 10
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (26926635..26933708)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (26964922..26971995)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 89 member B Neighboring gene EH domain binding protein 1-like 1b Neighboring gene endothelial zinc finger protein induced by tumor necrosis factor alpha-like Neighboring gene FERM domain containing 8

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC113919

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
RAB1B, member RAS oncogene family b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002129.2NP_001002129.2  RAB1B, member RAS oncogene family b

    See identical proteins and their annotated locations for NP_001002129.2

    Status: VALIDATED

    Source sequence(s)
    CR450793, EH444733, EH525664
    UniProtKB/TrEMBL
    A0A8M1MZW9, Q4V984
    Related
    ENSDARP00000073437.4, ENSDART00000078980.6
    Conserved Domains (2) summary
    smart00175
    Location:9172
    RAB; Rab subfamily of small GTPases
    cd01869
    Location:7172
    Rab1_Ypt1; Rab GTPase family 1 includes the yeast homolog Ypt1

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    26926635..26933708
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394787.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    154262..161354
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)