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ube2l3a ubiquitin-conjugating enzyme E2L 3a [ Danio rerio (zebrafish) ]

Gene ID: 415162, updated on 9-Dec-2024

Summary

Official Symbol
ube2l3aprovided by ZNC
Official Full Name
ubiquitin-conjugating enzyme E2L 3aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-2977
See related
Ensembl:ENSDARG00000112087 AllianceGenome:ZFIN:ZDB-GENE-030131-2977
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ube2l3; zgc:86727; wu:fc22h11
Summary
Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be active in nucleus. Is expressed in blastomere; brain; paraxial mesoderm; and somite. Orthologous to human UBE2L3 (ubiquitin conjugating enzyme E2 L3) and UBE2L5 (ubiquitin conjugating enzyme E2 L5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See ube2l3a in Genome Data Viewer
Location:
chromosome: 10
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (3133098..3138403, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (3052953..3058858)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene Ras protein-specific guanine nucleotide-releasing factor 2a Neighboring gene creatine kinase, mitochondrial 2a (sarcomeric) Neighboring gene hypermethylated in cancer 2 Neighboring gene phosphatidylinositol 4-kinase, catalytic, alpha a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin conjugating enzyme activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ubiquitin conjugating enzyme activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in protein polyubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
ubiquitin-conjugating enzyme E2 L3a
Names
ubiquitin-conjugating enzyme E2L 3
NP_001002072.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002072.2NP_001002072.1  ubiquitin-conjugating enzyme E2 L3a

    See identical proteins and their annotated locations for NP_001002072.1

    Status: VALIDATED

    Source sequence(s)
    EH549097, EH570970, EH575166
    UniProtKB/TrEMBL
    A0A8M1MZS9, Q6IQK2
    Related
    ENSDARP00000148914.1, ENSDART00000183365.1
    Conserved Domains (1) summary
    pfam00179
    Location:6144
    UQ_con; Ubiquitin-conjugating enzyme

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    3133098..3138403 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394799.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    32311..38216 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)