mthl5 methuselah-like 5 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: mthl5provided by FlyBase
Official Full Name: methuselah-like 5provided by FlyBase
Primary source: FLYBASE:FBgn0037960
Locus tag: Dmel_CG6965
See related: AllianceGenome:FB:FBgn0037960
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0170980.70; anon-WO0170980.71; CG6965; Dmel\CG6965; Gia; Mth-5; mth15; Mthl5
Summary: Predicted to enable G protein-coupled receptor activity. Involved in heart morphogenesis. Predicted to be located in membrane. Is expressed in several structures, including antennal anlage; cardiogenic mesoderm; central brain anlage; embryonic cardioblast; and ganglia. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (11883938..11887168, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (7709660..7712890, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables G protein-coupled receptor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in G protein-coupled receptor signaling pathway	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in cell surface receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in determination of adult lifespan	ISS Inferred from Sequence or Structural Similarity more info
involved_in heart morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to starvation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Names: CG6965-PA; CG6965-PB; GPCR in aorta; Methuselah-like 5; Mth-like 5; mthl5-PA; mthl5-PB

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