Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search NCBI

ClC-a - Chloride channel-a

Enables chloride channel activity. Involved in chloride transport and water transport. Located in apical plasma membrane and basal plasma membrane. Is expressed in several structures, including Malpighian tubule Type II cell; adult head; embryonic/larval midgut; ganglia; and glial cell. Used to study myopathy. Human ortholog(s) of this gene implicated in several diseases, including idiopathic generalized epilepsy 11; myotonia congenita (multiple); primary hyperaldosteronism; renal tubular transport disease (multiple); and sensorineural hearing loss. Orthologous to several human genes including CLCN2 (chloride voltage-gated channel 2). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to ClC-a

NCBI Orthologs

How was this calculated?

genes for:

Protein alignment

Align

Download data

Download
Species Gene Architecture aa