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CG5281 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41375, updated on 4-Jan-2025

Summary

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Official Symbol
CG5281provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0037902
Locus tag
Dmel_CG5281
See related
AllianceGenome:FB:FBgn0037902
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5281
Summary
Predicted to enable antiporter activity and nucleotide-sugar transmembrane transporter activity. Predicted to be involved in nucleotide-sugar transmembrane transport. Predicted to be active in membrane. Orthologous to human SLC35G1 (solute carrier family 35 member G1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG5281 in Genome Data Viewer
Location:
86E5-86E5; 3-51 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11435850..11437523)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7261572..7263245)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L24-like Neighboring gene D-aminoacyl-tRNA deacylase Neighboring gene uncharacterized protein Neighboring gene Exonuclease 3'-5' domain-containing 2 Neighboring gene uncharacterized protein Neighboring gene sarcomere length short Neighboring gene mir-4945 stem loop Neighboring gene Peptidoglycan recognition protein LB

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. miRISC recruits decapping factors to miRNA targets to enhance their degradation. Nishihara T, et al. Nucleic Acids Res, 2013 Oct. PMID 23863838, Free PMC Article
  2. Deadenylation is a widespread effect of miRNA regulation. Eulalio A, et al. RNA, 2009 Jan. PMID 19029310, Free PMC Article
  3. The β-alanine transporter BalaT is required for visual neurotransmission in Drosophila. Han Y, et al. Elife, 2017 Aug 14. PMID 28806173, Free PMC Article
  4. Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability. Dutta D, et al. Proc Natl Acad Sci U S A, 2024 Feb 27. PMID 38381787, Free PMC Article
  5. A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies. Ceder MM, et al. Gene, 2022 Jan 30. PMID 34673204

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables antiporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables nucleotide-sugar transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in nucleotide-sugar transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG5281-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    11435850..11437523
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141819.2 → NP_650076.1  uncharacterized protein Dmel_CG5281 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650076.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VGN6
    Related
    FBpp0081867
    Conserved Domains (3) summary
    COG0697
    Location:38 → 328
    RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
    pfam00892
    Location:38 → 169
    EamA; EamA-like transporter family
    cl23754
    Location:189 → 324
    EamA; EamA-like transporter family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VGN6 Q9VGN6

Gene LinkOut

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