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ninaG ninaG [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41369, updated on 9-Dec-2024

Summary

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Official Symbol
ninaGprovided by FlyBase
Official Full Name
ninaGprovided by FlyBase
Primary source
FLYBASE:FBgn0037896
Locus tag
Dmel_CG6728
See related
AllianceGenome:FB:FBgn0037896
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6728; Dmel\CG6728; NinaG
Summary
Enables oxidoreductase activity. Involved in several processes, including protein localization to rhabdomere; rhabdomere morphogenesis; and rhodopsin metabolic process. Is expressed in adult head; lch5 scolopidial ligament cell; and scolopidial ligament cell. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See ninaG in Genome Data Viewer
Location:
86E5-86E5; 3-51 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11419376..11421693, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7245098..7247415, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene brother of rumpel Neighboring gene uncharacterized protein Neighboring gene Spastizin Neighboring gene Ribosomal protein L24-like Neighboring gene D-aminoacyl-tRNA deacylase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The role of Drosophila ninaG oxidoreductase in visual pigment chromophore biogenesis. Ahmad ST, et al. J Biol Chem, 2006 Apr 7. PMID 16464863
  2. Heterologous expression of bovine rhodopsin in Drosophila photoreceptor cells. Ahmad ST, et al. Invest Ophthalmol Vis Sci, 2006 Sep. PMID 16936079
  3. The Drosophila ninaG oxidoreductase acts in visual pigment chromophore production. Sarfare S, et al. J Biol Chem, 2005 Mar 25. PMID 15640158
  4. Chromophore-Independent Roles of Opsin Apoproteins in Drosophila Mechanoreceptors. Katana R, et al. Curr Biol, 2019 Sep 9. PMID 31447373
  5. Regulation of ecdysteroid signalling during Drosophila development: identification, characterization and modelling of ecdysone oxidase, an enzyme involved in control of ligand concentration. Takeuchi H, et al. Biochem J, 2005 Aug 1. PMID 15813704, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables oxidoreductase activity, acting on CH-OH group of donors IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein localization to rhabdomere IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in retinoid metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in rhabdomere morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in rhodopsin metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in visual perception IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
ninaG
Names
CG6728-PA
CG6728-PB
ninaG-PA
ninaG-PB
NP_001247047.1
NP_650070.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    11419376..11421693 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001260118.1 → NP_001247047.1  ninaG, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247047.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8MSH3, Q9VGP2
    UniProtKB/TrEMBL
    A0A0B4K737
    Conserved Domains (3) summary
    COG2303
    Location:72 → 572
    BetA; Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]
    pfam05199
    Location:419 → 566
    GMC_oxred_C; GMC oxidoreductase
    cl21454
    Location:119 → 311
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. NM_141813.2 → NP_650070.1  ninaG, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650070.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VGP2
    Related
    FBpp0081880, FBtr0082404
    Conserved Domains (3) summary
    COG2303
    Location:72 → 588
    BetA; Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]
    pfam05199
    Location:435 → 582
    GMC_oxred_C; GMC oxidoreductase
    cl21454
    Location:119 → 327
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4K737 A0A0B4K737
Q9VGP2.2 Q9VGP2

Gene LinkOut

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