mgr merry-go-round [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: mgrprovided by FlyBase
Official Full Name: merry-go-roundprovided by FlyBase
Primary source: FLYBASE:FBgn0264694
Locus tag: Dmel_CG6719
See related: AllianceGenome:FB:FBgn0264694
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:LD34406; CG6719; Dmel\CG6719; Mgr; PAC10; Pfdn3
Summary: Enables beta-tubulin binding activity. Involved in establishment or maintenance of neuroblast polarity and microtubule cytoskeleton organization. Located in cytoplasm. Part of prefoldin complex. Orthologous to human VBP1 (VHL binding protein 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (11408792..11409875, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (7234514..7235597, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables beta-tubulin binding	IDA Inferred from Direct Assay more info	PubMed
enables tubulin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in centrosome cycle	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in establishment or maintenance of neuroblast polarity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in meiotic spindle assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in microtubule-based process	IBA Inferred from Biological aspect of Ancestor more info
involved_in microtubule-based process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitotic spindle assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein folding	IEA Inferred from Electronic Annotation more info
involved_in tubulin complex assembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
part_of prefoldin complex	IBA Inferred from Biological aspect of Ancestor more info
part_of prefoldin complex	IDA Inferred from Direct Assay more info	PubMed
part_of prefoldin complex	IEA Inferred from Electronic Annotation more info