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KP78b KP78b [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41361, updated on 4-Jan-2025

Summary

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Official Symbol
KP78bprovided by FlyBase
Official Full Name
KP78bprovided by FlyBase
Primary source
FLYBASE:FBgn0026063
Locus tag
Dmel_CG17216
See related
AllianceGenome:FB:FBgn0026063
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG17216; Dmel\CG17216; Kp78b; Kp78B; KP78B
Summary
Predicted to enable tau-protein kinase activity. Predicted to be involved in intracellular signal transduction and microtubule cytoskeleton organization. Predicted to be active in cytoplasm. Is expressed in mesoderm. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See KP78b in Genome Data Viewer
Location:
86E2-86E2; 3-51 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11346294..11353131, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7172016..7178853, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45055 Neighboring gene long non-coding RNA:CR46008 Neighboring gene prospero Neighboring gene long non-coding RNA:CR46009 Neighboring gene long non-coding RNA:CR46010 Neighboring gene KP78a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. LKB1 regulates polarity remodeling and adherens junction formation in the Drosophila eye. Amin N, et al. Proc Natl Acad Sci U S A, 2009 Jun 2. PMID 19443685, Free PMC Article
  2. The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole. Shulman JM, et al. Cell, 2000 May 12. PMID 10830165
  3. Drosophila LKB1 is required for the assembly of the polarized actin structure that allows spermatid individualization. Couderc JL, et al. PLoS One, 2017. PMID 28767695, Free PMC Article
  4. Genes encoding novel secreted and transmembrane proteins are temporally and spatially regulated during Drosophila melanogaster embryogenesis. Zúñiga A, et al. BMC Biol, 2009 Sep 22. PMID 19772636, Free PMC Article
  5. Computation-based discovery of related transcriptional regulatory modules and motifs using an experimentally validated combinatorial model. Halfon MS, et al. Genome Res, 2002 Jul. PMID 12097338, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables tau-protein kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
KP78b
Names
CG17216-PA
CG17216-PB
KP78b-PA
KP78b-PB
NP_001163587.1
NP_650065.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    11346294..11353131 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001170116.2 → NP_001163587.1  KP78b, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163587.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T473, Q9VGQ0
    Conserved Domains (2) summary
    smart00220
    Location:63 → 314
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:63 → 314
    PKc_like; Protein Kinases, catalytic domain

  2. NM_141808.4 → NP_650065.1  KP78b, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650065.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T473, Q9VGQ0
    Related
    FBpp0081884
    Conserved Domains (2) summary
    smart00220
    Location:63 → 314
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:63 → 314
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O17049 O17049
Q8T473 Q8T473
Q9VGQ0 Q9VGQ0

Gene LinkOut

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