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RpL3 Ribosomal protein L3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41347, updated on 4-Jan-2025

Summary

Official Symbol
RpL3provided by FlyBase
Official Full Name
Ribosomal protein L3provided by FlyBase
Primary source
FLYBASE:FBgn0020910
Locus tag
Dmel_CG4863
See related
AllianceGenome:FB:FBgn0020910
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-EST:GressD4; CG4863; chr3R:7047878..7048035; Dmel\CG4863; L3; rpL3; Rpl3
Summary
A structural constituent of ribosome. Predicted to be involved in translation. Located in cytosolic ribosome. Is expressed in several structures, including adult head; adult heart; clypeo-labral primordium; embryonic/larval midgut primordium; and gut section. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2D. Orthologous to several human genes including RPL3 (ribosomal protein L3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See RpL3 in Genome Data Viewer
Location:
86D8-86D8; 3-50 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11221894..11225173)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7047616..7050895)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene antisense RNA:CR31144 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SCP-containing protein C Neighboring gene uncharacterized protein Neighboring gene GRIP and coiled-coil domain containing 88 kDa

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
involved_in cytoplasmic translation IC
Inferred by Curator
more info
PubMed 
involved_in cytoplasmic translation TAS
Traceable Author Statement
more info
PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of cytosolic large ribosomal subunit TAS
Traceable Author Statement
more info
PubMed 
located_in cytosolic ribosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ribosomal protein L3
Names
CG4863-PA
CG4863-PD
CG4863-PG
CG4863-PH
RpL3-PA
RpL3-PD
RpL3-PG
RpL3-PH

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    11221894..11225173
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_169378.2NP_731548.2  ribosomal protein L3, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_731548.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O16797, Q0KI83, Q6NNE9, Q9VGR4, Q9VGR5, Q9VGR6
    UniProtKB/TrEMBL
    C6SUV6
    Conserved Domains (1) summary
    PTZ00103
    Location:1400
    PTZ00103; 60S ribosomal protein L3; Provisional
  2. NM_169380.2NP_731550.2  ribosomal protein L3, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_731550.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O16797
    Conserved Domains (1) summary
    PTZ00103
    Location:1121
    PTZ00103; 60S ribosomal protein L3; Provisional
  3. NM_079592.3NP_524316.1  ribosomal protein L3, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524316.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O16797, Q0KI83, Q6NNE9, Q9VGR4, Q9VGR5, Q9VGR6
    UniProtKB/TrEMBL
    C6SUV6
    Related
    FBpp0081822
    Conserved Domains (1) summary
    PTZ00103
    Location:1400
    PTZ00103; 60S ribosomal protein L3; Provisional
  4. NM_169377.2NP_731547.1  ribosomal protein L3, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_731547.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O16797
    Related
    FBpp0081823
    Conserved Domains (1) summary
    cl00324
    Location:3118
    RplC; Ribosomal protein L3 [Translation, ribosomal structure and biogenesis]