SdhC - Succinate dehydrogenase, subunit C
Predicted to enable electron transfer activity. Involved in determination of adult lifespan; mitochondrial electron transport, succinate to ubiquinone; and response to oxidative stress. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex II (succinate dehydrogenase). Is expressed in several structures, including Malpighian tubule primordium; adult head; adult heart; embryonic/larval midgut primordium; and gut section. Human ortholog(s) of this gene implicated in Carney-Stratakis syndrome; gastrointestinal stromal tumor; lung non-small cell carcinoma; and paraganglioma. Orthologous to human SDHC (succinate dehydrogenase complex subunit C). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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