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Desi Desiccate [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41292, updated on 9-Dec-2024

Summary

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Official Symbol
Desiprovided by FlyBase
Official Full Name
Desiccateprovided by FlyBase
Primary source
FLYBASE:FBgn0037832
Locus tag
Dmel_CG14686
See related
AllianceGenome:FB:FBgn0037832
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG14686; Dmel\CG14686
Summary
Predicted to enable PDZ domain binding activity and SH2 domain binding activity. Involved in response to desiccation and sensory perception of taste. Located in apical part of cell. Is expressed in several structures, including assembly zone; embryonic/larval mouth; epidermis; labellar cap; and sense organ. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Desi in Genome Data Viewer
Location:
86C6-86C6; 3-50 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (10779569..10780825)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (6605291..6606547)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Chromosome associated protein H2 Neighboring gene Transcription factor TFIIFbeta Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene fau Neighboring gene uncharacterized protein Neighboring gene mitochondrial ribosomal protein L37

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Function of desiccate in gustatory sensilla of drosophila melanogaster. Kawano T, et al. Sci Rep, 2015 Nov 27. PMID 26610608, Free PMC Article
  2. Identification of a gene, Desiccate, contributing to desiccation resistance in Drosophila melanogaster. Kawano T, et al. J Biol Chem, 2010 Dec 10. PMID 20937803, Free PMC Article
  3. Genetic architecture of natural variation in cuticular hydrocarbon composition in Drosophila melanogaster. Dembeck LM, et al. Elife, 2015 Nov 14. PMID 26568309, Free PMC Article
  4. Correlation between desiccation stress response and epigenetic modifications of genes in Drosophila melanogaster: An example of environment-epigenome interaction. Sharma V, et al. Biochim Biophys Acta Gene Regul Mech, 2017 Oct. PMID 28801151
  5. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables PDZ domain binding ISM
Inferred from Sequence Model
more info
 PubMed 
enables SH2 domain binding ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in response to desiccation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sensory perception of taste IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in apical part of cell IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
desiccate
Names
CG14686-PA
Desi-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    10779569..10780825
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141759.4 → NP_650016.1  desiccate [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650016.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VGX0
    Related
    FBpp0081751
    Conserved Domains (1) summary
    pfam07841
    Location:142 → 226
    DM4_12; DM4/DM12 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VGX0 Q9VGX0

Gene LinkOut

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