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CG9393 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41152, updated on 9-Dec-2024

Summary

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Official Symbol
CG9393provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0037710
Locus tag
Dmel_CG9393
See related
AllianceGenome:FB:FBgn0037710
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG9393
Summary
Predicted to be involved in protein insertion into mitochondrial outer membrane. Located in mitochondrial outer membrane. Is expressed in adult head and organism. Orthologous to human MTX1 (metaxin 1) and MTX3 (metaxin 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG9393 in Genome Data Viewer
Location:
85D24-85D25; 3-48 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9561583..9563673, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5387305..5389395, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Branched chain keto acid dehydrogenase E1 subunit alpha Neighboring gene Adaptor Protein complex 1, mu subunit Neighboring gene Methyl-CpG binding domain protein-like Neighboring gene Vacuolar protein sorting 45 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Illuminating the role of caspases during Drosophila oogenesis. Mazzalupo S, et al. Cell Death Differ, 2006 Nov. PMID 16528381
  2. Evolution and structural organization of the mitochondrial contact site (MICOS) complex and the mitochondrial intermembrane space bridging (MIB) complex. Huynen MA, et al. Biochim Biophys Acta, 2016 Jan. PMID 26477565
  3. Vesicular transport mediates the uptake of cytoplasmic proteins into mitochondria in Drosophila melanogaster. Chen PL, et al. Nat Commun, 2020 May 22. PMID 32444642, Free PMC Article
  4. Endogenously imprinted genes in Drosophila melanogaster. McEachern LA, et al. Mol Genet Genomics, 2014 Aug. PMID 24658702
  5. Erect wing regulates synaptic growth in Drosophila by integration of multiple signaling pathways. Haussmann IU, et al. Genome Biol, 2008 Apr 17. PMID 18419806, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in mitochondrion organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrion organization IEA
Inferred from Electronic Annotation
more info
  
involved_in protein insertion into mitochondrial outer membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of SAM complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SAM complex IEA
Inferred from Electronic Annotation
more info
  
part_of SAM complex ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG9393-PA
CG9393-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    9561583..9563673 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141651.3 → NP_649908.1  uncharacterized protein Dmel_CG9393, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649908.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VHB6
    Related
    FBpp0081591
    Conserved Domains (2) summary
    cd03212
    Location:108 → 244
    GST_C_Metaxin1_3; C-terminal, alpha helical domain of Metaxin 1, Metaxin 3, and similar proteins
    cd03078
    Location:8 → 79
    GST_N_Metaxin1_like; GST_N family, Metaxin subfamily, Metaxin 1-like proteins; composed of metaxins 1 and 3, and similar proteins including Tom37 from fungi. Mammalian metaxin (or metaxin 1) and the fungal protein Tom37 are components of preprotein import complexes of the ...

  2. NM_001275493.1 → NP_001262422.1  uncharacterized protein Dmel_CG9393, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262422.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KGL6
    Conserved Domains (2) summary
    cd03212
    Location:108 → 244
    GST_C_Metaxin1_3; C-terminal, alpha helical domain of Metaxin 1, Metaxin 3, and similar proteins
    cd03078
    Location:8 → 79
    GST_N_Metaxin1_like; GST_N family, Metaxin subfamily, Metaxin 1-like proteins; composed of metaxins 1 and 3, and similar proteins including Tom37 from fungi. Mammalian metaxin (or metaxin 1) and the fungal protein Tom37 are components of preprotein import complexes of the ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4KGL6 A0A0B4KGL6
Q9VHB6.1 Q9VHB6

Gene LinkOut

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