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MBD-like - Methyl-CpG binding domain protein-like

Enables several functions, including histone deacetylase binding activity; methyl-CpG binding activity; and protein homodimerization activity. Involved in chromosome condensation and negative regulation of DNA-templated transcription. Located in nucleus and polytene chromosome. Part of NuRD complex. Is expressed in several structures, including gonad and male germline cell. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to several human genes including MBD3 (methyl-CpG binding domain protein 3). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa