tgo - tango
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; myosin binding activity; and protein heterodimerization activity. Involved in several processes, including imaginal disc-derived leg joint morphogenesis; nervous system development; and regulation of transcription by RNA polymerase II. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including embryonic head segment; ganglia; glial cell; presumptive embryonic/larval system; and tracheal primordium. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human ARNT (aryl hydrocarbon receptor nuclear translocator) and ARNT2 (aryl hydrocarbon receptor nuclear translocator 2). [provided by Alliance of Genome Resources, Nov 2024]
NCBI Orthologs
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Protein alignment
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