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hng2 hinge2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41056, updated on 9-Dec-2024

Summary

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Official Symbol
hng2provided by FlyBase
Official Full Name
hinge2provided by FlyBase
Primary source
FLYBASE:FBgn0037634
Locus tag
Dmel_CG8359
See related
AllianceGenome:FB:FBgn0037634
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8359; Dmel\CG8359
Summary
Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including antennal primordium; central brain primordium; ganglia; head epidermis primordium; and ventral nerve cord primordium. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See hng2 in Genome Data Viewer
Location:
85B2-85B2; 3-48 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8806322..8807581)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4632044..4633303)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene PFTAIRE-interacting factor 1B Neighboring gene PFTAIRE-interacting factor 1A Neighboring gene Ionotropic receptor 85a Neighboring gene Chaperonin containing TCP1 subunit 7 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43130 Neighboring gene aaquetzalli

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Stonewall and Brickwall: Two Partially Redundant Determinants Required for the Maintenance of Female Germline in Drosophila. Shukla V, et al. G3 (Bethesda), 2018 May 31. PMID 29669801, Free PMC Article
  2. Gene duplication, lineage-specific expansion, and subfunctionalization in the MADF-BESS family patterns the Drosophila wing hinge. Shukla V, et al. Genetics, 2014 Feb. PMID 24336749, Free PMC Article
  3. Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live Drosophila. Bischof J, et al. Elife, 2018 Sep 24. PMID 30247122, Free PMC Article
  4. A Comprehensive Drosophila melanogaster Transcription Factor Interactome. Shokri L, et al. Cell Rep, 2019 Apr 16. PMID 30995488, Free PMC Article
  5. A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development. Schertel C, et al. Genome Res, 2015 Apr. PMID 25568052, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription regulator complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
hinge2
Names
CG8359-PA
hng2-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    8806322..8807581
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141580.3 → NP_649837.1  hinge2 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649837.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VHL0
    Related
    FBpp0081402
    Conserved Domains (2) summary
    pfam02944
    Location:216 → 250
    BESS; BESS motif
    pfam10545
    Location:21 → 113
    MADF_DNA_bdg; Alcohol dehydrogenase transcription factor Myb/SANT-like
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VHL0 Q9VHL0

Gene LinkOut

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