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mRpL19 mitochondrial ribosomal protein L19 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41028, updated on 4-Jan-2025

Summary

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Official Symbol
mRpL19provided by FlyBase
Official Full Name
mitochondrial ribosomal protein L19provided by FlyBase
Primary source
FLYBASE:FBgn0037608
Locus tag
Dmel_CG8039
See related
AllianceGenome:FB:FBgn0037608
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8039; Dmel\CG8039; L19; mRPL19; RpL19
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is expressed in several structures, including Malpighian tubule primordium; adult head; embryonic/larval midgut primordium; gut section; and larval somatic muscle cell. Orthologous to human MRPL19 (mitochondrial ribosomal protein L19). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See mRpL19 in Genome Data Viewer
Location:
85A5-85A5; 3-48 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8674109..8675196)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4499831..4500918)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene pink Neighboring gene transfer RNA:Tyrosine-GTA 1-7 Neighboring gene transfer RNA:Tyrosine-GTA 1-8 Neighboring gene uncharacterized protein Neighboring gene Unc50 RNA binding protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3. Gajan A, et al. Epigenetics Chromatin, 2016. PMID 26848313, Free PMC Article
  2. Loss of the SIN3 transcriptional corepressor results in aberrant mitochondrial function. Barnes VL, et al. BMC Biochem, 2010 Jul 9. PMID 20618965, Free PMC Article
  3. Cardiomyopathy is associated with ribosomal protein gene haplo-insufficiency in Drosophila melanogaster. Casad ME, et al. Genetics, 2011 Nov. PMID 21890737, Free PMC Article
  4. Protein synthesis and degradation are essential to regulate germline stem cell homeostasis in Drosophila testes. Yu J, et al. Development, 2016 Aug 15. PMID 27471256
  5. Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. Suzuki T, et al. J Biol Chem, 2001 Jun 15. PMID 11279069

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome ISS
Inferred from Sequence or Structural Similarity
more info
  
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation TAS
Traceable Author Statement
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
part_of mitochondrial large ribosomal subunit TAS
Traceable Author Statement
more info
 PubMed 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitochondrial ribosomal protein L19
Names
CG8039-PA
mRpL19-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    8674109..8675196
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079560.5 → NP_524284.1  mitochondrial ribosomal protein L19 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524284.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VHN6
    Related
    FBpp0081384
    Conserved Domains (1) summary
    cl00406
    Location:94 → 183
    Ribosomal_L19; Ribosomal protein L19
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VHN6.1 Q9VHN6

Gene LinkOut

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