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SLIRP2 SRA stem-loop interacting RNA binding protein 2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41021, updated on 4-Jan-2025

Summary

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Official Symbol
SLIRP2provided by FlyBase
Official Full Name
SRA stem-loop interacting RNA binding protein 2provided by FlyBase
Primary source
FLYBASE:FBgn0037602
Locus tag
Dmel_CG8021
See related
AllianceGenome:FB:FBgn0037602
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
cg8021; CG8021; Dmel\CG8021; DmSLIRP2
Summary
Predicted to enable mRNA binding activity. Involved in regulation of mitochondrial transcription. Is active in mitochondrial matrix. Orthologous to human SLIRP (SRA stem-loop interacting RNA binding protein). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See SLIRP2 in Genome Data Viewer
Location:
85A5-85A5; 3-48 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8651084..8651493)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4476806..4477215)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Cytochrome P450 313b1 Neighboring gene MAP kinase kinase 4 Neighboring gene Dihydroorotate dehydrogenase Neighboring gene Sys1 golgi trafficking protein Neighboring gene uncharacterized protein Neighboring gene belle

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation. Baggio F, et al. Nucleic Acids Res, 2014 Dec 16. PMID 25428350, Free PMC Article
  2. Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Mummery-Widmer JL, et al. Nature, 2009 Apr 23. PMID 19363474, Free PMC Article
  3. Genome-wide RNAi screen identifies networks involved in intestinal stem cell regulation in Drosophila. Zeng X, et al. Cell Rep, 2015 Feb 24. PMID 25704823, Free PMC Article
  4. The drosophila melanogaster genome: translation factors and RNA binding proteins. Lasko P. J Cell Biol, 2000 Jul 24. PMID 10908586, Free PMC Article
  5. Screen for mitochondrial DNA copy number maintenance genes reveals essential role for ATP synthase. Fukuoh A, et al. Mol Syst Biol, 2014 Jun 21. PMID 24952591, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mRNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of mitochondrial transcription IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
is_active_in mitochondrial matrix IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SRA stem-loop interacting RNA binding protein 2
Names
CG8021-PA
SLIRP2-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    8651084..8651493
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141551.2 → NP_649808.1  SRA stem-loop interacting RNA binding protein 2 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649808.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3DNE9, Q9VHP3
    Related
    FBpp0081367
    Conserved Domains (1) summary
    cd12242
    Location:11 → 83
    RRM_SLIRP; RNA recognition motif found in SRA stem-loop-interacting RNA-binding protein (SLIRP) and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VHP3 Q9VHP3

Gene LinkOut

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