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CG9727 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40794, updated on 4-Jan-2025

Summary

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Official Symbol
CG9727provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0037445
Locus tag
Dmel_CG9727
See related
AllianceGenome:FB:FBgn0037445
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG9727
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in organism. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder and severe combined immunodeficiency. Orthologous to human RFX5 (regulatory factor X5) and RFX7 (regulatory factor X7). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG9727 in Genome Data Viewer
Location:
83E7-83E8; 3-47.5 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6449944..6456676, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2275666..2282398, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Dementin Neighboring gene long non-coding RNA:CR44017 Neighboring gene grappa Neighboring gene mir-9375 stem loop Neighboring gene Zinc-finger protein Neighboring gene neurochondrin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Spatial expression of transcription factors in Drosophila embryonic organ development. Hammonds AS, et al. Genome Biol, 2013 Dec 20. PMID 24359758, Free PMC Article
  2. Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. Krauchunas AR, et al. Dev Biol, 2012 Oct 1. PMID 22884528, Free PMC Article
  3. Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library. Lowe N, et al. Development, 2014 Oct. PMID 25294943, Free PMC Article
  4. A Comprehensive Drosophila melanogaster Transcription Factor Interactome. Shokri L, et al. Cell Rep, 2019 Apr 16. PMID 30995488, Free PMC Article
  5. In vivo analysis of proteomes and interactomes using Parallel Affinity Capture (iPAC) coupled to mass spectrometry. Rees JS, et al. Mol Cell Proteomics, 2011 Jun. PMID 21447707, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG9727-PA
CG9727-PB
CG9727-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    6449944..6456676 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275389.1 → NP_001262318.1  uncharacterized protein Dmel_CG9727, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262318.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VI23
    Conserved Domains (1) summary
    pfam02257
    Location:307 → 383
    RFX_DNA_binding; RFX DNA-binding domain

  2. NM_141399.3 → NP_649656.1  uncharacterized protein Dmel_CG9727, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649656.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VI23
    Related
    FBpp0081227
    Conserved Domains (1) summary
    pfam02257
    Location:307 → 383
    RFX_DNA_binding; RFX DNA-binding domain

  3. NM_001275388.1 → NP_001262317.1  uncharacterized protein Dmel_CG9727, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262317.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KGM5
    Conserved Domains (1) summary
    pfam02257
    Location:307 → 383
    RFX_DNA_binding; RFX DNA-binding domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4KGM5 A0A0B4KGM5
Q9VI23 Q9VI23

Gene LinkOut

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