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CG18048 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40782, updated on 9-Dec-2024

Summary

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Official Symbol
CG18048provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0037435
Locus tag
Dmel_CG18048
See related
AllianceGenome:FB:FBgn0037435
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG18048
Summary
Predicted to enable tRNA 2'-O-methyltransferase activity. Predicted to be involved in tRNA methylation. Is expressed in organism. Orthologous to human TRMT13 (tRNA methyltransferase 13 homolog). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG18048 in Genome Data Viewer
Location:
83E4-83E4; 3-47.5 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6346111..6347519)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2171833..2173241)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Small ribonucleoprotein particle protein SmD2 Neighboring gene Hormone receptor 83 Neighboring gene p21-activated kinase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
  2. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
  3. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
  4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
  5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables tRNA 2'-O-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA 2'-O-methyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables tRNA methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in tRNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tRNA methylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG18048-PA
NP_649646.3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    6346111..6347519
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141389.4 → NP_649646.3  uncharacterized protein Dmel_CG18048 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649646.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SX24, Q9VI11
    Related
    FBpp0081209
    Conserved Domains (3) summary
    pfam05206
    Location:183 → 429
    TRM13; Methyltransferase TRM13
    pfam05253
    Location:69 → 92
    zf-U11-48K; U11-48K-like CHHC zinc finger
    pfam11722
    Location:20 → 44
    zf-TRM13_CCCH; CCCH zinc finger in TRM13 protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SX24 Q8SX24

Gene LinkOut

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