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gpn2 GPN-loop GTPase 2 [ Danio rerio (zebrafish) ]

Gene ID: 407722, updated on 4-Jan-2025

Summary

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Official Symbol
gpn2provided by ZNC
Official Full Name
GPN-loop GTPase 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-041010-86
See related
Ensembl:ENSDARG00000103127 AllianceGenome:ZFIN:ZDB-GENE-041010-86
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
atpbd1b; zgc:92877
Summary
Predicted to enable GTPase activity. Orthologous to human GPN2 (GPN-loop GTPase 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See gpn2 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (33938213..33943728)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (33984047..33989698)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene G protein nucleolar 2 Neighboring gene dynein, axonemal, light intermediate chain 1 Neighboring gene Smad nuclear interacting protein Neighboring gene AT-rich interaction domain 1Aa Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class V

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Prepatterning of developmental gene expression by modified histones before zygotic genome activation. Lindeman LC, et al. Dev Cell, 2011 Dec 13. PMID 22137762
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC92877

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
GPN-loop GTPase 2
Names
ATP-binding domain 1 family member B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_214801.2 → NP_999966.2  GPN-loop GTPase 2

    See identical proteins and their annotated locations for NP_999966.2

    Status: VALIDATED

    Source sequence(s)
    BC083538, BC152270, EB797177
    UniProtKB/Swiss-Prot
    Q5XIY1, Q6PUR6
    UniProtKB/TrEMBL
    A0A8M3AJ98, A7MCQ6
    Related
    ENSDARP00000138851.1, ENSDART00000166254.2
    Conserved Domains (2) summary
    COG1100
    Location:14 → 183
    Gem1; GTPase SAR1 family domain [General function prediction only]
    pfam03029
    Location:15 → 262
    ATP_bind_1; Conserved hypothetical ATP binding protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    33938213..33943728
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009292455.4 → XP_009290730.1  GPN-loop GTPase 2 isoform X1

    See identical proteins and their annotated locations for XP_009290730.1

    UniProtKB/Swiss-Prot
    Q5XIY1, Q6PUR6
    UniProtKB/TrEMBL
    A0A8M3AJ98, A7MCQ6
    Related
    ENSDART00000162704.2
    Conserved Domains (2) summary
    COG1100
    Location:14 → 183
    Gem1; GTPase SAR1 family domain [General function prediction only]
    pfam03029
    Location:15 → 262
    ATP_bind_1; Conserved hypothetical ATP binding protein
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6PUR6.1 GenPept UniProtKB/Swiss-Prot:Q6PUR6

Gene LinkOut

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