atg14 autophagy related 14 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: atg14provided by ZNC
Official Full Name: autophagy related 14provided by ZNC
Primary source: ZFIN:ZDB-GENE-050913-155
See related: Ensembl:ENSDARG00000002670 AllianceGenome:ZFIN:ZDB-GENE-050913-155
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:113944
Summary: Predicted to enable phosphatidylinositol 3-kinase regulator activity and protein-membrane adaptor activity. Predicted to be involved in cellular response to starvation and macroautophagy. Predicted to be located in cytoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex, class III. Predicted to be active in autophagosome. Predicted to be extrinsic component of omegasome membrane and extrinsic component of phagophore assembly site membrane. Orthologous to human ATG14 (autophagy related 14). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (10748412..10766345)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (10592378..10610649)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables phosphatidylinositol 3-kinase regulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein-membrane adaptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in autophagosome assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in autophagosome membrane docking	IBA Inferred from Biological aspect of Ancestor more info
involved_in cellular response to starvation	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitophagy	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in autophagosome	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in extrinsic component of omegasome membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in extrinsic component of phagophore assembly site membrane	IBA Inferred from Biological aspect of Ancestor more info
part_of phosphatidylinositol 3-kinase complex, class III	IBA Inferred from Biological aspect of Ancestor more info
part_of protein-containing complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: beclin 1-associated autophagy-related key regulator

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.