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nvl nuclear VCP like [ Danio rerio (zebrafish) ]

Gene ID: 406805, updated on 9-Dec-2024

Summary

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Official Symbol
nvlprovided by ZNC
Official Full Name
nuclear VCP likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2871
See related
Ensembl:ENSDARG00000025605 AllianceGenome:ZFIN:ZDB-GENE-040426-2871
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:55732; wu:fa20g10
Summary
Predicted to enable ATP hydrolysis activity and preribosome binding activity. Predicted to be involved in ribosome biogenesis. Predicted to be active in nucleus. Orthologous to human NVL (nuclear VCP like). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See nvl in Genome Data Viewer
Location:
chromosome: 13
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (516258..533220, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (385967..402929, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene F-box protein 28 Neighboring gene delta(4)-desaturase, sphingolipid 1 Neighboring gene wu:fc17b08 Neighboring gene slit homolog 1a (Drosophila)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables preribosome binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in anatomical structure morphogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosome biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
nuclear valosin-containing protein-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213484.1 → NP_998649.1  nuclear valosin-containing protein-like

    See identical proteins and their annotated locations for NP_998649.1

    Status: PROVISIONAL

    Source sequence(s)
    BC044464
    UniProtKB/TrEMBL
    Q803I9
    Related
    ENSDARP00000032193.8, ENSDART00000038315.9
    Conserved Domains (5) summary
    COG0464
    Location:246 → 792
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
    pfam00004
    Location:557 → 687
    AAA; ATPase family associated with various cellular activities (AAA)
    pfam08208
    Location:165 → 215
    RNA_polI_A34; DNA-directed RNA polymerase I subunit RPA34.5
    pfam16725
    Location:2 → 71
    Nucleolin_bd; Nucleolin binding domain
    cl21455
    Location:537 → 573
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    516258..533220 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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