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sh3bp5b SH3-domain binding protein 5b (BTK-associated) [ Danio rerio (zebrafish) ]

Gene ID: 406767, updated on 4-Jan-2025

Summary

Official Symbol
sh3bp5bprovided by ZNC
Official Full Name
SH3-domain binding protein 5b (BTK-associated)provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2813
See related
Ensembl:ENSDARG00000103978 AllianceGenome:ZFIN:ZDB-GENE-040426-2813
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sh3bp5; zgc:55565; wu:fj55c06
Summary
Predicted to enable protein kinase inhibitor activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. Is expressed in intermediate cell mass of mesoderm and male organism. Orthologous to human SH3BP5 (SH3 domain binding protein 5). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See sh3bp5b in Genome Data Viewer
Location:
chromosome: 16
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (36126973..36163267)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (36118324..36154618)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene organic solute carrier partner 1b Neighboring gene mitochondrial ribosomal protein S15 Neighboring gene calpain 7 Neighboring gene uncharacterized LOC137487301

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
SH3 domain-binding protein 5b
Names
SH3-domain binding protein 5 (BTK-associated)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213458.1NP_998623.1  SH3 domain-binding protein 5b

    See identical proteins and their annotated locations for NP_998623.1

    Status: PROVISIONAL

    Source sequence(s)
    BC044426
    UniProtKB/TrEMBL
    Q803L6
    Related
    ENSDARP00000132176.1, ENSDART00000166040.2
    Conserved Domains (1) summary
    pfam05276
    Location:22244
    SH3BP5; SH3 domain-binding protein 5 (SH3BP5)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    36126973..36163267
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)