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med21 mediator complex subunit 21 [ Danio rerio (zebrafish) ]

Gene ID: 406732, updated on 4-Jan-2025

Summary

Official Symbol
med21provided by ZNC
Official Full Name
mediator complex subunit 21provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2763
See related
Ensembl:ENSDARG00000026839 AllianceGenome:ZFIN:ZDB-GENE-040426-2763
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
surb7; fk48d02; zgc:56532; wu:fk48d02
Summary
Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of mediator complex. Orthologous to human MED21 (mediator complex subunit 21). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See med21 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (1757487..1759555)
105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (1908174..1910242)

Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene FGFR1 oncogene partner 2 Neighboring gene transmembrane 7 superfamily member 3 Neighboring gene peptidase, mitochondrial processing subunit beta Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 2 Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 4b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of mediator complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mediator complex IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mediator of RNA polymerase II transcription subunit 21
Names
RNA polymerase II holoenzyme component SRB7
RNAPII complex component SRB7
SRB7 suppressor of RNA polymerase B homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213423.1NP_998588.1  mediator of RNA polymerase II transcription subunit 21

    See identical proteins and their annotated locations for NP_998588.1

    Status: PROVISIONAL

    Source sequence(s)
    BC049042
    UniProtKB/Swiss-Prot
    Q7ZTI5
    Related
    ENSDARP00000036773.6, ENSDART00000032460.7
    Conserved Domains (1) summary
    pfam11221
    Location:1127
    Med21; Subunit 21 of Mediator complex

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007115.7 Reference GRCz11 Primary Assembly

    Range
    1757487..1759555
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)