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myl9b myosin, light chain 9b, regulatory [ Danio rerio (zebrafish) ]

Gene ID: 406493, updated on 4-Jan-2025

Summary

Official Symbol
myl9bprovided by ZNC
Official Full Name
myosin, light chain 9b, regulatoryprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2296
See related
Ensembl:ENSDARG00000008030 AllianceGenome:ZFIN:ZDB-GENE-040426-2296
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
myl9; zgc:77916
Summary
Predicted to enable myosin heavy chain binding activity. Predicted to be involved in myofibril assembly. Predicted to be part of myosin II complex. Predicted to be active in myofibril and stress fiber. Is expressed in smooth muscle cell. Human ortholog(s) of this gene implicated in familial hypertrophic cardiomyopathy and megacystis-microcolon-intestinal hypoperistalsis syndrome. Orthologous to human MYL9 (myosin light chain 9). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See myl9b in Genome Data Viewer
Location:
chromosome: 6
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (1787280..1799330)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (1652141..1664191)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene zgc:113442 Neighboring gene N-terminal asparagine amidase Neighboring gene homeobox protein TGIF2 Neighboring gene discs, large (Drosophila) homolog-associated protein 4b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables myosin heavy chain binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in myofibril assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in myofibril IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of myosin II complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in stress fiber IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
myosin regulatory light polypeptide 9b
Names
myl9l
myosin, light polypeptide 9, regulatory

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213212.1NP_998377.1  myosin regulatory light polypeptide 9b

    See identical proteins and their annotated locations for NP_998377.1

    Status: PROVISIONAL

    Source sequence(s)
    BC068220
    UniProtKB/TrEMBL
    A0A8M1PES6, A0A8M9PKQ2, F1QYK9, Q6NVA6
    Related
    ENSDARP00000104211.2, ENSDART00000113505.5
    Conserved Domains (1) summary
    COG5126
    Location:19169
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    1787280..1799330
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)