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Btnl8 butyrophilin-like 8 [ Rattus norvegicus (Norway rat) ]

Gene ID: 406160, updated on 27-Nov-2024

Summary

Symbol
Btnl8provided by RGD
Full Name
butyrophilin-like 8provided by RGD
Primary source
RGD:1303010
See related
EnsemblRapid:ENSRNOG00000064738 AllianceGenome:RGD:1303010
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 4.7), Spleen (RPKM 3.3) and 6 other tissues See more
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Genomic context

See Btnl8 in Genome Data Viewer
Location:
20p12
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (4268823..4282807)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (4264840..4280876)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (2845720..2863449, complement)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene complement C4B Neighboring gene cytochrome P450, family 21, subfamily a, polypeptide 1, pseudogene Neighboring gene butyrophilin-like 4 Neighboring gene butyrophilin-like 7 Neighboring gene butyrophilin-like 6, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in T cell receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of cytokine production IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of immune response TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
butyrophilin-like 8
Names
butyrophilin subfamily 1 member A1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001395869.1NP_001382798.1  butyrophilin-like 8

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000020
    UniProtKB/TrEMBL
    A0A8J8XT05
    Related
    ENSRNOP00000098197.2, ENSRNOT00000120556.2
    Conserved Domains (2) summary
    smart00409
    Location:3589
    IG; Immunoglobulin
    cd13733
    Location:288445
    SPRY_PRY_C-I_1; PRY/SPRY domain in tripartite motif-containing (TRIM) proteins, including TRIM5, TRIM6, TRIM7, TRIM10, TRIM11, TRIM17, TRIM20, TRIM21, TRIM27, TRIM35, TRIM38, TRIM41, TRIM50, TRIM58, TRIM60, TRIM62, TRIM69, TRIM72, NF7 and bloodthirsty

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    4268823..4282807
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063279340.1XP_063135410.1  butyrophilin-like 8 isoform X1

  2. XM_063279344.1XP_063135414.1  butyrophilin-like 8 isoform X4

  3. XM_063279339.1XP_063135409.1  butyrophilin-like 8 isoform X1

    Related
    ENSRNOP00000034566.7, ENSRNOT00000029409.8
  4. XM_063279345.1XP_063135415.1  butyrophilin-like 8 isoform X5

  5. XM_063279341.1XP_063135411.1  butyrophilin-like 8 isoform X2

  6. XM_063279342.1XP_063135412.1  butyrophilin-like 8 isoform X3

  7. XM_063279346.1XP_063135416.1  butyrophilin-like 8 isoform X6

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001395863.1: Suppressed sequence

    Description
    NM_001395863.1: This RefSeq was removed because currently there is insufficient support for the transcript.
  2. NM_212489.1: Suppressed sequence

    Description
    NM_212489.1: This RefSeq was removed because currently there is insufficient support for the transcript.