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plscr3b phospholipid scramblase 3b [ Danio rerio (zebrafish) ]

Gene ID: 405802, updated on 9-Dec-2024

Summary

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Official Symbol
plscr3bprovided by ZNC
Official Full Name
phospholipid scramblase 3bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2517
See related
Ensembl:ENSDARG00000069432 AllianceGenome:ZFIN:ZDB-GENE-040426-2517
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:77051
Summary
Predicted to enable phospholipid scramblase activity. Predicted to be involved in plasma membrane phospholipid scrambling. Predicted to be active in plasma membrane. Is expressed in several structures, including blastomere; ectoderm; epidermis; intermediate cell mass of mesoderm; and nervous system. Orthologous to several human genes including PLSCR2 (phospholipid scramblase 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See plscr3b in Genome Data Viewer
Location:
chromosome: 7
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (26581644..26603484, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (26311163..26332277, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene tyrosine kinase, non-receptor, 1 Neighboring gene si:dkey-62k3.6 Neighboring gene PHD finger protein 23b Neighboring gene heat shock factor binding protein 1a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Analyses of mRNA structure dynamics identify embryonic gene regulatory programs. Beaudoin JD, et al. Nat Struct Mol Biol, 2018 Aug. PMID 30061596, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC77051

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables phospholipid scramblase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phospholipid scramblase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in plasma membrane phospholipid scrambling IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within plasma membrane phospholipid scrambling IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
phospholipid scramblase 3b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212866.1 → NP_998031.1  phospholipid scramblase 3b

    See identical proteins and their annotated locations for NP_998031.1

    Status: PROVISIONAL

    Source sequence(s)
    BC066765
    UniProtKB/TrEMBL
    A0A8M1PFW8, Q6NY24
    Related
    ENSDARP00000089774.3, ENSDART00000099003.6
    Conserved Domains (2) summary
    pfam03803
    Location:80 → 302
    Scramblase; Scramblase
    cl25887
    Location:4 → 94
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    26581644..26603484 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068222204.1 → XP_068078305.1  phospholipid scramblase 3b isoform X2

    UniProtKB/TrEMBL
    A0A8M9QGS0

  2. XM_021477454.2 → XP_021333129.1  phospholipid scramblase 3b isoform X1

    UniProtKB/TrEMBL
    A0A8M1PFW8, Q6NY24
    Related
    ENSDARP00000153626.1, ENSDART00000188934.1
    Conserved Domains (2) summary
    pfam03803
    Location:80 → 302
    Scramblase; Scramblase
    cl25887
    Location:4 → 94
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  3. XM_068222205.1 → XP_068078306.1  phospholipid scramblase 3b isoform X2

    UniProtKB/TrEMBL
    A0A8M9QGS0
Nucleotide Protein
Heading Accession and Version

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