Vps24 Vacuolar protein sorting 24 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Vps24provided by FlyBase
Official Full Name: Vacuolar protein sorting 24provided by FlyBase
Primary source: FLYBASE:FBgn0037231
Locus tag: Dmel_CG9779
See related: AllianceGenome:FB:FBgn0037231
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG9779; Dmel\CG9779; DmVPS24; dvps24; ESCRT; vps24
Summary: Predicted to be involved in several processes, including endosome transport via multivesicular body sorting pathway; intralumenal vesicle formation; and late endosome to vacuole transport. Predicted to be part of ESCRT III complex. Predicted to be active in multivesicular body. Is expressed in several structures, including adult head; embryonic dorsal epidermis; embryonic ventral epidermis; ganglia; and larval nervous system. Orthologous to human RNF103-CHMP3 (RNF103-CHMP3 readthrough) and CHMP3 (charged multivesicular body protein 3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (4307435..4310947, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (135369..136669, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Genetic analysis of the Drosophila ESCRT-III complex protein, VPS24, reveals a novel function in lysosome homeostasis.
Title: Genetic analysis of the Drosophila ESCRT-III complex protein, VPS24, reveals a novel function in lysosome homeostasis.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in endosome transport via multivesicular body sorting pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in intralumenal vesicle formation	ISS Inferred from Sequence or Structural Similarity more info
involved_in late endosome to vacuole transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in vacuolar transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of ESCRT III complex	IBA Inferred from Biological aspect of Ancestor more info
part_of ESCRT III complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed
is_active_in multivesicular body	IBA Inferred from Biological aspect of Ancestor more info

Names: CG9779-PA; CG9779-PB; Vps24-PA; Vps24-PB; charged multivesicular body protein 3

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The following sections contain reference sequences that belong to a specific genome build. Explain