DhpD Dihydropterin deaminase [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: DhpDprovided by FlyBase
Official Full Name: Dihydropterin deaminaseprovided by FlyBase
Primary source: FLYBASE:FBgn0261436
Locus tag: Dmel_CG18143
See related: AllianceGenome:FB:FBgn0261436
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG18143; Dmel\CG18143
Summary: Enables dihydropterin deaminase activity and guanine deaminase activity. Involved in dihydropteridine metabolic process; eye pigment biosynthetic process; and guanine metabolic process. Predicted to be active in cytosol. Is expressed in adult head; embryonic/larval fat body; and organism. Orthologous to human GDA (guanine deaminase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (4227387..4229238, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (53109..54960, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Dihydropterin deaminase encoded by CG18143 plays a role in the biosynthesis of aurodrosopterin.
Title: Guanine deaminase functions as dihydropterin deaminase in the biosynthesis of aurodrosopterin, a minor red eye pigment of Drosophila.

Submit: New GeneRIF Correction

Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Function	Evidence Code	Pubs
enables dihydropterin deaminase activity	IDA Inferred from Direct Assay more info	PubMed
enables guanine deaminase activity	IBA Inferred from Biological aspect of Ancestor more info
enables guanine deaminase activity	IDA Inferred from Direct Assay more info	PubMed
enables guanine deaminase activity	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in dihydropteridine metabolic process	IDA Inferred from Direct Assay more info
involved_in dihydropteridine metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in eye pigment biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in guanine catabolic process	IEA Inferred from Electronic Annotation more info
involved_in guanine metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in guanine metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

NP_649439.1

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The following sections contain reference sequences that belong to a specific genome build. Explain