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Ten-m - Tenascin major

Enables filamin binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in several processes, including neuron development; regulation of cell-cell adhesion; and synapse organization. Located in neuromuscular junction; neuronal cell body; and postsynaptic membrane. Is expressed in several structures, including adult sense organ; epithelium; imaginal disc; region of integument; and sensory system neurons. Human ortholog(s) of this gene implicated in cocaine dependence and essential tremor 5. Orthologous to several human genes including TENM1 (teneurin transmembrane protein 1); TENM2 (teneurin transmembrane protein 2); and TENM3 (teneurin transmembrane protein 3). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa