Oat Ornithine aminotransferase precursor [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Oatprovided by FlyBase
Official Full Name: Ornithine aminotransferase precursorprovided by FlyBase
Primary source: FLYBASE:FBgn0022774
Locus tag: Dmel_CG8782
See related: AllianceGenome:FB:FBgn0022774
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 151832_at; CG8782; Dmel\CG8782
Summary: Predicted to enable identical protein binding activity; ornithine aminotransferase activity; and pyridoxal phosphate binding activity. Predicted to be involved in arginine catabolic process to glutamate; arginine catabolic process to proline via ornithine; and ornithine metabolic process. Located in mitochondrion. Is expressed in adult head; adult heart; amnioserosa; embryonic/larval fat body; and yolk nucleus. Human ortholog(s) of this gene implicated in gyrate atrophy. Orthologous to human OAT (ornithine aminotransferase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (19647280..19649851, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (19640380..19642951, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables identical protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables ornithine aminotransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables ornithine aminotransferase activity	IEA Inferred from Electronic Annotation more info
enables ornithine aminotransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables pyridoxal phosphate binding	IBA Inferred from Biological aspect of Ancestor more info
enables pyridoxal phosphate binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in arginine catabolic process to glutamate	IBA Inferred from Biological aspect of Ancestor more info
involved_in arginine catabolic process to proline via ornithine	IBA Inferred from Biological aspect of Ancestor more info
involved_in ornithine metabolic process	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrial matrix	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed

NP_649139.1

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The following sections contain reference sequences that belong to a specific genome build. Explain