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Lon - Lon protease

Enables serine hydrolase activity. Involved in mitochondrion organization and positive regulation of protein catabolic process. Located in mitochondrion. Is expressed in several structures, including Malpighian tubule primordium; adult head; embryonic/larval midgut primordium; gut section; and mesoderm. Used to study CODAS syndrome. Human ortholog(s) of this gene implicated in CODAS syndrome. Orthologous to human LONP1 (lon peptidase 1, mitochondrial). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa