Gem2 Gemin 2 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Gem2provided by FlyBase
Official Full Name: Gemin 2provided by FlyBase
Primary source: FLYBASE:FBgn0036850
Locus tag: Dmel_CG10419
See related: AllianceGenome:FB:FBgn0036850
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG10419; dGem2; Dmel\CG10419
Summary: Involved in flight behavior and spliceosomal snRNP assembly. Part of several cellular components, including SMN complex; SMN-Gemin2 complex; and SmD-containing SMN-Sm protein complex. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; central brain primordium; embryonic/larval midgut primordium; and female germline cell. Orthologous to human GEMIN2 (gem nuclear organelle associated protein 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (19099123..19100363, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (19092223..19093463, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in adult locomotory behavior	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in flight behavior	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein-RNA complex assembly	IDA Inferred from Direct Assay more info	PubMed
involved_in spliceosomal complex assembly	IEA Inferred from Electronic Annotation more info
involved_in spliceosomal snRNP assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in spliceosomal snRNP assembly	IDA Inferred from Direct Assay more info	PubMed
involved_in spliceosomal snRNP assembly	IEA Inferred from Electronic Annotation more info
involved_in spliceosomal snRNP assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of SMN complex	IBA Inferred from Biological aspect of Ancestor more info
part_of SMN complex	IDA Inferred from Direct Assay more info	PubMed
part_of SMN complex	IGI Inferred from Genetic Interaction more info	PubMed
part_of SMN-Gemin2 complex	IDA Inferred from Direct Assay more info	PubMed
part_of SmD-containing SMN-Sm protein complex	IDA Inferred from Direct Assay more info	PubMed
part_of cytoplasmic U snRNP body	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of spliceosomal complex	IEA Inferred from Electronic Annotation more info

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